⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180416 | 0.97 | — | — | |
| SCHEMBL3549230 | 0.97 | — | — | |
| SCHEMBL3544580 | 0.97 | — | — | |
| SCHEMBL3548123 | 0.97 | — | — | |
| SCHEMBL3544932 | 0.97 | — | — | |
| SCHEMBL1010984 | 0.90 | — | — | |
| SCHEMBL11758797 | 0.90 | — | — | |
| SCHEMBL4013 | 0.90 | — | — | |
| SCHEMBL3540541 | 0.80 | — | — | |
| SCHEMBL3548345 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117534663-A | Fused tricyclic derivatives and their pharmaceutical use | 正大天晴药业集团股份有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-116457357-A | Fused tricyclic derivatives and their pharmaceutical use | 正大天晴药业集团股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-115867541-A | Aminopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-03-28 | — | — | CN | claimed |
| EP-3652184-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | AbbVie Inc. (US) | 2020-05-20 | — | — | EP | claimed |
| CN-111093645-A | Selective inhibitors of clinically important mutants of EGFR tyrosine kinase | CS制药技术有限公司 | 2020-05-01 | — | — | CN | claimed |
| WO-2019035911-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | ABBVIE INC. (US) | 2019-02-21 | — | — | WO | claimed |
| WO-2016123709-A1 | FLUORINATED IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AS INHIBITORS OF BROMODOMAIN CONTAINING PROTEINS | TRILLIUM THERAPEUTICS INC. (CA) | 2016-08-11 | — | — | WO | claimed |
| EP-3788053-B1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | AMGEN INC (US) | 2024-07-10 | — | — | EP | disclosed |
| CN-118317960-A | Pyrazolo ring compounds and uses thereof | 海南康哲美丽科技有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118317958-A | Tri-fused ring derivative and preparation method and application thereof | 上海济煜医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-113906017-B | Isoquinoline ketone derivative as ROCK protein kinase inhibitor and application thereof | 广州润尔眼科生物科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118255834-A | Ring-modified proline short peptide compound and application thereof | 福建广生中霖生物科技有限公司 | 2024-06-28 | — | — | CN | disclosed |
| US-20240208945-A1 | 6-CARBAMATE SUBSTITUTED HETEROARYL RING DERIVATIVES | MEDSHINE DISCOVERY INC. (CN) | 2024-06-27 | — | — | US | disclosed |
| EP-1140811-A1 | NOVEL HERBICIDES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037437-A1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-06-29 | — | — | WO | disclosed |
| WO-1996000219-A1 | PYRIMIDINYL- AND TRIAZINYL-OXY AND THIO-3-HALOALKYL-PROPIONIC ACID DERIVATIVES AS HERBICIDES | CIBA-GEIGY AG (CH) | 1996-01-04 | — | — | WO | disclosed |
| US-5455355-A | Postemergence, preemergence herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-03 | — | — | US | disclosed |
| US-5298632-A | Herbicidal pyrimidine compounds, compositions containing the same and method of use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5232897-A | Herbicidal pyrimidine compounds, compositions containing the same and method of use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0457505-A2 | Pyrimidine derivatives and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-11-21 | — | — | EP | disclosed |