Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.58 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6125719 | 0.93 | HMGCR (0.51) | HMGCRGPR84SPHK1FFAR1LMNA | |
| SCHEMBL736276 | 0.92 | HMGCR (0.53) | HMGCRSPHK1LMNA | |
| SCHEMBL6137642 | 0.91 | HMGCR (0.51) | HMGCRPTPN7GPR84SPHK1FFAR1 | |
| Acetic Acid SCHEMBL10540684 | 0.91 | HMGCR (0.63) | HMGCRPTPN7GPR84FFAR1 | |
| SCHEMBL6137648 | 0.91 | HMGCR (0.51) | HMGCRPTPN7GPR84SPHK1FFAR1 | |
| SCHEMBL31682154 | 0.87 | HMGCR (0.46) | HMGCRPTPN7 | |
| SCHEMBL10912609 | 0.87 | HMGCR (0.46) | HMGCRPTPN7 | |
| SCHEMBL12003762 | 0.86 | HMGCR (0.45) | HMGCRPTPN7 | |
| SCHEMBL10540678 | 0.86 | HMGCR (0.81) | HMGCRPTPN7GPR84FFAR1 | |
| SCHEMBL10540677 | 0.86 | HMGCR (0.81) | HMGCRPTPN7GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169033-B1 | INHIBITORS OF SLOW REACTING SUBSTANCE OF ANAPHYLAXIS | SCHERING CORPORATION (US) | 1992-02-12 | — | — | EP | disclosed |
| EP-0169033-A2 | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |