Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.61 |
| ▸ | TK2 | O00142 | 3/20 | 0.54 |
| ▸ | TK1 | P04183 | 4/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22875773 | 1.00 | ABCG2 (0.61) | ABCG2ABCB1TK2TK1BCHE | |
| SCHEMBL9355402 | 0.87 | ABCG2 (0.52) | ABCG2ABCB1TK1BCHE | |
| SCHEMBL26049446 | 0.87 | ABCG2 (0.54) | ABCG2ABCB1TK1BCHE | |
| SCHEMBL27815893 | 0.87 | ABCG2 (0.54) | ABCG2ABCB1TK1BCHE | |
| SCHEMBL22837953 | 0.85 | ABCG2 (0.54) | ABCG2ABCB1TK2TK1BCHE | |
| SCHEMBL5360913 | 0.83 | ABCG2 (0.68) | ABCG2ABCB1TK2TK1 | |
| SCHEMBL5367768 | 0.83 | ABCG2 (0.68) | ABCG2ABCB1TK2TK1 | |
| SCHEMBL2056737 | 0.83 | ABCG2 (0.68) | ABCG2ABCB1TK2TK1 | |
| SCHEMBL5358026 | 0.83 | ABCG2 (0.68) | ABCG2ABCB1TK2TK1 | |
| SCHEMBL1145611 | 0.83 | ABCG2 (0.68) | ABCG2ABCB1TK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2941437-A1 | PREPARATIONS OF HYDROPHOBIC THERAPEUTIC AGENTS, METHODS OF MANUFACTURE AND USE THEREOF | Aciex Therapeutics, Inc. (US) | 2015-11-11 | — | — | EP | disclosed |
| WO-2014107231-A1 | PREPARATIONS OF HYDROPHOBIC THERAPEUTIC AGENTS, METHODS OF MANUFACTURE AND USE THEREOF | ACIEX THERAPEUTICS, INC. (US) | 2014-07-10 | — | — | WO | disclosed |
| EP-0366171-B1 | NUCLEOSIDE DERIVATIVES | NYCOMED AS (NO) | 1992-05-06 | — | — | EP | disclosed |
| EP-0366171-A1 | Nucleoside derivatives | NYCOMED AS (NO) | 1990-05-02 | — | — | EP | disclosed |