SCHEMBL9626745

CC(C)(C)[Si](C)(C)OCCCCCCCCCCC[C@@H]1CC2=CC(=O)CC[C@@H]2[C@H]2CC[C@]3(C)C(=O)CC[C@H]3[C@H]12

nearest known ligand 0.48

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	CYP19A1	P11511	13/20	0.48

▸	AR	P10275	6/20	0.42

▸	PGR	P06401	5/20	0.42

▸	NR3C2	P08235	2/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9626846	1.00	CYP19A1 (0.48)	CYP19A1ARPGRNR3C2
SCHEMBL7025460	1.00	CYP19A1 (0.48)	CYP19A1ARPGRNR3C2
SCHEMBL9627566	1.00	CYP19A1 (0.48)	CYP19A1ARPGRNR3C2
SCHEMBL6849006	0.85	CYP19A1 (0.36)	CYP19A1AR
SCHEMBL9626851	0.84	CYP19A1 (0.49)	CYP19A1ARPGRNR3C2
SCHEMBL7030182	0.84	CYP19A1 (0.49)	CYP19A1ARPGRNR3C2
SCHEMBL9626840	0.84	CYP19A1 (0.46)	CYP19A1ARPGRNR3C2
SCHEMBL9626738	0.84	CYP19A1 (0.46)	CYP19A1ARPGRNR3C2
SCHEMBL9627560	0.84	CYP19A1 (0.46)	CYP19A1ARPGRNR3C2
SCHEMBL7020267	0.83	CYP19A1 (0.55)	CYP19A1ARPGRNR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5145847-A	Antiestrogens	SCHERING AKTIENGESELLSCHAFT (DE)	1992-09-08	—	—	US	disclosed