Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.56 |
| ▸ | RARB | P10826 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627339 | 0.90 | PTPN11 (0.55) | PTPN11RARBMAPTTP53TSHR | |
| SCHEMBL10583502 | 0.90 | PTPN11 (0.55) | PTPN11RARBMAPTTP53TSHR | |
| SCHEMBL10396856 | 0.88 | PTPN11 (0.56) | PTPN11RARBMAPTTP53TSHR | |
| SCHEMBL9541986 | 0.86 | PTPN11 (0.57) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL10587295 | 0.86 | NPC1 (0.49) | PTPN11RARBMAPTTP53TSHR | |
| SCHEMBL9627193 | 0.86 | NPC1 (0.49) | PTPN11RARBMAPTTP53TSHR | |
| SCHEMBL10397746 | 0.86 | NPC1 (0.49) | PTPN11RARBMAPTTP53TSHR | |
| SCHEMBL9627334 | 0.86 | NPC1 (0.49) | PTPN11RARBMAPTTP53TSHR | |
| SCHEMBL9627524 | 0.86 | NPC1 (0.49) | PTPN11RARBMAPTTP53TSHR | |
| SCHEMBL9627574 | 0.86 | NPC1 (0.49) | PTPN11RARBMAPTTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188222-B1 | NOVEL LIQUID CRISTALLINE COMPOUNDS HAVING SUBSTITUENTS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-4943386-A | FERROELECTRIC, GOOD RESPONSE AND MEMORY | DAINIPPON INK & CHEMICALS, INC. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4828754-A | TILT-TYPE CHIRAL SMECTIC PHASE | DAINIPPON INK & CHEMICALS, INC. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0188222-A2 | Novel liquid cristalline compounds having substituents | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1986-07-23 | — | — | EP | disclosed |