Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15536424 | 0.88 | TSHR (0.41) | TSHRHPGDTHRBTHRAHCAR2 | |
| SCHEMBL15536449 | 0.85 | TSHR (0.39) | TSHRHPGDTHRBTHRAHCAR2 | |
| SCHEMBL15536651 | 0.84 | TSHR (0.38) | TSHRHPGDTHRBTHRA | |
| SCHEMBL31742398 | 0.81 | TSHR (0.50) | TSHRHPGDTHRBTHRAHCAR2 | |
| SCHEMBL25277800 | 0.80 | TSHR (0.39) | TSHRHPGDTHRBTHRAHCAR2 | |
| SCHEMBL7649093 | 0.79 | TSHR (0.48) | TSHRHPGDTHRBTHRAHCAR2 | |
| SCHEMBL18134827 | 0.79 | TSHR (0.48) | TSHRHPGDTHRBTHRAHCAR2 | |
| SCHEMBL7125959 | 0.79 | TSHR (0.48) | TSHRHPGDTHRBTHRAHCAR2 | |
| SCHEMBL21647292 | 0.79 | TSHR (0.48) | TSHRHPGDTHRBTHRAHCAR2 | |
| SCHEMBL17851213 | 0.79 | TSHR (0.48) | TSHRHPGDTHRBTHRAHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226387-B1 | COATING RESIN COMPOSITION | Hitachi Chemical Co., Ltd. (JP) | 1992-03-04 | — | — | EP | claimed |
| US-4795785-A | CHLORINATED OLEFIN, UNSATURATED ORGANIC SILANE COMPOUND, (METH)ACRYLATE POLYMER | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1989-01-03 | — | — | US | claimed |
| EP-0226387-A2 | Coating resin composition | Hitachi Chemical Co., Ltd. (JP) | 1987-06-24 | — | — | EP | claimed |
| EP-0226387-B1 | COATING RESIN COMPOSITION | Hitachi Chemical Co., Ltd. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4795785-A | CHLORINATED OLEFIN, UNSATURATED ORGANIC SILANE COMPOUND, (METH)ACRYLATE POLYMER | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1989-01-03 | — | — | US | disclosed |
| EP-0226387-A2 | Coating resin composition | Hitachi Chemical Co., Ltd. (JP) | 1987-06-24 | — | — | EP | disclosed |