Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9627482

CCCCCCCCN.N.O=P(O)(O)CCCCP(=O)(O)O

nearest known ligand 0.75

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 3/20 0.75
LPAR2 Q9HBW0 1/20 0.75
LMNA P02545 1/20 0.60
CYP3A4 P08684 1/20 0.60
NFKB1 P19838 1/20 0.60
BLM P54132 1/20 0.60
PMP22 Q01453 1/20 0.60
GABBR2 O75899 1/20 0.55
GABRR1 P24046 1/20 0.55
GABBR1 Q9UBS5 1/20 0.55
S1PR2 O95136 6/20 0.55
S1PR1 P21453 6/20 0.55
S1PR3 Q99500 6/20 0.55
S1PR4 O95977 5/20 0.55
S1PR5 Q9H228 2/20 0.55
DNM1 Q05193 5/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
ALDH1A1 P00352 1/20 0.54
TSHR P16473 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL9626557 1.00 LPAR3 (0.75) LPAR3LPAR2LMNACYP3A4NFKB1
Octadecylamine SCHEMBL28268234 0.98 LPAR3 (0.78) LPAR3LPAR2LMNACYP3A4NFKB1
Dodecylamine SCHEMBL6575795 0.91 LPAR3 (0.67) LPAR3LPAR2LMNACYP3A4NFKB1
Butylamine SCHEMBL9627493 0.91 LPAR3 (0.67) LPAR3LPAR2LMNACYP3A4NFKB1
Ammonia Solution, Strong SCHEMBL23037455 0.89 LPAR3 (0.95) LPAR3LPAR2S1PR2S1PR1S1PR3
Ammonia Solution, Strong SCHEMBL23037782 0.89 LPAR3 (0.95) LPAR3LPAR2S1PR2S1PR1S1PR3
Ammonia Solution, Strong SCHEMBL23037457 0.89 LPAR3 (0.95) LPAR3LPAR2S1PR2S1PR1S1PR3
Ammonia Solution, Strong SCHEMBL23037458 0.89 LPAR3 (0.95) LPAR3LPAR2S1PR2S1PR1S1PR3
Ammonia Solution, Strong SCHEMBL23037456 0.89 LPAR3 (0.95) LPAR3LPAR2S1PR2S1PR1S1PR3
Ammonia Solution, Strong SCHEMBL22975036 0.89 LPAR3 (0.95) LPAR3LPAR2S1PR2S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0275215-B1 CONTRAST AGENTS FOR THE GASTROINTESTINAL TRACT GUERBET S.A. (FR) 1992-04-08 EP disclosed
EP-0275215-A1 Contrast agents for the gastrointestinal tract GUERBET S.A. (FR) 1988-07-20 EP disclosed