SCHEMBL9628142

SCHEMBL9628142

CCCCN(CCCC)CON(CC)CC

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.34
CA1 P00915 3/20 0.34
CA9 Q16790 3/20 0.34
MAPT P10636 1/20 0.31
KCNH2 Q12809 2/20 0.31
CA2 P00918 1/20 0.30
HTR1D P28221 1/20 0.30
HTR1B P28222 1/20 0.30
KDM5A P29375 1/20 0.30
KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL347977 0.79 CA12 (0.39) CA12CA1CA9MAPTKCNH2
SCHEMBL2497623 0.72 CA12 (0.36) CA12CA1CA9MAPTHTR1B
SCHEMBL347018 0.70 CA12 (0.34) CA12CA1CA9MAPTHTR1B
SCHEMBL2497255 0.70 CA12 (0.34) CA12CA1CA9MAPTKDM5A
SCHEMBL28121805 0.70 CA12 (0.32) CA12CA1CA9CA2
SCHEMBL22725 0.70
SCHEMBL217114 0.70 KCNH2 (0.47) CA12CA1CA9MAPTKCNH2
SCHEMBL3904839 0.69 TSHR (0.46) CA12CA1CA9MAPTKDM5A
SCHEMBL27566038 0.69 TSHR (0.46) CA12CA1CA9MAPTKDM5A
SCHEMBL896 0.69 TSHR (0.46) CA12CA1CA9MAPTKDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0246189-B1 COMPOSITIONS STABILIZED BY AMINOXYALKYL AMINES CIBA-GEIGY AG (CH) 1992-03-11 EP claimed
US-4757102-A For stabilizing plastic, polymer, or resin subject to oxidative, thermal and actinic degradation CIBA-GEIGY CORPORATION (US) 1988-07-12 US claimed
EP-0246189-A2 Compositions stabilized by aminoxyalkyl amines CIBA-GEIGY AG (CH) 1987-11-19 EP claimed
EP-0246189-B1 COMPOSITIONS STABILIZED BY AMINOXYALKYL AMINES CIBA-GEIGY AG (CH) 1992-03-11 EP disclosed
US-4757102-A For stabilizing plastic, polymer, or resin subject to oxidative, thermal and actinic degradation CIBA-GEIGY CORPORATION (US) 1988-07-12 US disclosed
EP-0246189-A2 Compositions stabilized by aminoxyalkyl amines CIBA-GEIGY AG (CH) 1987-11-19 EP disclosed