SCHEMBL9628284

SCHEMBL9628284

CCC(C)C1=CC(=O)c2ccccc2C1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.52
SOAT1 P35610 13/20 0.50
S100A4 P26447 3/20 0.50
IDO1 P14902 2/20 0.50
CDC25A P30304 2/20 0.50
CDC25B P30305 2/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
MEN1 O00255 1/20 0.50
PLIN1 O60240 1/20 0.50
NR1I2 O75469 1/20 0.50
USP2 O75604 1/20 0.50
ALDH1A1 P00352 1/20 0.50
GSR P00390 1/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28549609 0.98 PTPN1 (0.50) PTPN1SOAT1S100A4IDO1CDC25A
SCHEMBL25954040 0.86 SOAT1 (0.49) PTPN1SOAT1S100A4IDO1CDC25A
SCHEMBL18877803 0.85 PTPN1 (0.43) PTPN1SOAT1S100A4IDO1CDC25A
Ammonia Solution, Strong SCHEMBL28553028 0.84 SOAT1 (0.47) PTPN1SOAT1S100A4IDO1CDC25A
SCHEMBL25954041 0.83 IDO1 (0.52) PTPN1SOAT1S100A4IDO1CDC25A
Ammonia Solution, Strong SCHEMBL28570579 0.81 SOAT1 (0.50) PTPN1SOAT1S100A4IDO1CDC25A
SCHEMBL10446585 0.81 PTPN1 (0.47) PTPN1SOAT1S100A4IDO1CDC25A
SCHEMBL9627646 0.80 PTPN1 (0.70) PTPN1SOAT1S100A4IDO1CDC25A
SCHEMBL30038980 0.80 PTPN1 (0.70) PTPN1SOAT1S100A4IDO1CDC25A
SCHEMBL5810766 0.80 PTPN1 (0.59) PTPN1SOAT1S100A4IDO1CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023149432-A1 COMPOSITION CONTAINING FLUORINE-CONTAINING MONOMER, METHOD FOR STABILIZING FLUORINE-CONTAINING MONOMER, METHOD FOR MANUFACTURING FLUORINE-CONTAINING POLYMER, AND METHOD FOR MANUFACTURING FLUORINE-CONTAINING MONOMER ダイキン工業株式会社 2023-08-10 WO disclosed
US-5155132-A Nonsteroidal antiinflammatory agents; treating psoriasis SYNTEX (U.S.A.) INC. (US) 1992-10-13 US disclosed
US-5134161-A Enzyme inhibitors for skin disorders, antiinflammatory agents SYNTEX (U.S.A.) INC. (US) 1992-07-28 US disclosed
US-5089657-A Topical antiinflammatory agents SYNTEX (U.S.A.) INC. (US) 1992-02-18 US disclosed
US-4786652-A TOPICAL ADMINISTRATION SYNTEX (U.S.A.) INC. (US) 1988-11-22 US disclosed
EP-0282056-A2 Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-09-14 EP disclosed
EP-0282006-A1 Naphtalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-09-14 EP disclosed
US-4758587-A Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-07-19 US disclosed