Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MPL | P40238 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.43 |
| ▸ | TUBB | P07437 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17765084 | 0.84 | EP300 (0.55) | EP300KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9628098 | 0.84 | EP300 (0.51) | EP300KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9629408 | 0.84 | EP300 (0.51) | EP300KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9628147 | 0.84 | EP300 (0.51) | EP300KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9628240 | 0.84 | EP300 (0.56) | EP300KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL17765085 | 0.83 | KDM4E (0.58) | EP300KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29741571 | 0.83 | KDM4E (0.58) | EP300KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9628320 | 0.83 | MAPT (0.67) | EP300KDM4EALDH1A1MAPTTP53 | |
| SCHEMBL9054405 | 0.82 | EP300 (0.67) | EP300KDM4EALDH1A1MAPK1MAPT | |
| SCHEMBL29700325 | 0.82 | EP300 (0.67) | EP300KDM4EALDH1A1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | claimed |
| CN-103635837-A | Polarizing photochromic articles | TRANSITIONS OPTICAL INC | 2014-03-12 | — | — | CN | disclosed |
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |