Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994987 | 1.00 | NPC1 (0.47) | NPC1RAB9ACNR2CNR1POLB | |
| SCHEMBL29407323 | 1.00 | NPC1 (0.47) | NPC1RAB9ACNR2CNR1POLB | |
| SCHEMBL10743175 | 1.00 | NPC1 (0.47) | NPC1RAB9ACNR2CNR1POLB | |
| SCHEMBL9628354 | 1.00 | NPC1 (0.47) | NPC1RAB9ACNR2CNR1POLB | |
| SCHEMBL9628860 | 1.00 | NPC1 (0.47) | NPC1RAB9ACNR2CNR1POLB | |
| SCHEMBL9628497 | 1.00 | NPC1 (0.47) | NPC1RAB9ACNR2CNR1POLB | |
| SCHEMBL1532693 | 0.95 | NPC1 (0.49) | NPC1RAB9ACNR2CNR1POLB | |
| SCHEMBL605640 | 0.87 | NPC1 (0.37) | NPC1RAB9ACNR2CNR1ADORA3 | |
| SCHEMBL10474022 | 0.87 | NPC1 (0.42) | NPC1RAB9APOLBTYRADORA3 | |
| SCHEMBL38926 | 0.87 | NPC1 (0.56) | NPC1RAB9APOLBTYRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189374-B1 | LIQUID MIXTURES OF 2-(HYDROXY-3-BRANCHED ALKYL-5-METHYLPHENYL)-2H-BENZOTRIAZOLE, PROCESS FOR THEIR PREPARATION AND STABILIZED COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |
| US-4675352-A | PHOTOSTABILITY | CIBA-GEIGY CORPORATION (US) | 1987-06-23 | — | — | US | disclosed |
| EP-0189374-A2 | Liquid mixtures of 2-(hydroxy-3-branched alkyl-5-methylphenyl)-2H-benzotriazole, process for their preparation and stabilized compositions containing them | CIBA-GEIGY AG (CH) | 1986-07-30 | — | — | EP | disclosed |
| US-4587346-A | ALKYLATION WITH ALKENE AND ACID CATALYST | CIBA-GEIGY CORPORATION (US) | 1986-05-06 | — | — | US | disclosed |