Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13545695 | 0.98 | HTR2C (0.44) | HTR2CNOTUMHTR1APTGS2HTR7 | |
| SCHEMBL16951463 | 0.92 | HTR2C (0.48) | HTR2CNOTUMHTR1ATAS1R3TAS1R1 | |
| SCHEMBL20081001 | 0.88 | HTR2C (0.40) | HTR2CNOTUMHTR1APTGS2TAS1R3 | |
| SCHEMBL20312053 | 0.86 | OPRL1 (0.37) | HTR2CNOTUMOPRL1ALOX5APFEN1 | |
| SCHEMBL10030799 | 0.84 | OPRL1 (0.38) | HTR2CPTGS2OPRL1ALOX5APFEN1 | |
| SCHEMBL14591158 | 0.83 | HTR2C (0.42) | HTR2CNOTUMHTR1ASLC6A2SLC6A4 | |
| SCHEMBL12716351 | 0.82 | OPRL1 (0.40) | HTR2CNOTUMPTGS2OPRL1ALOX5AP | |
| SCHEMBL6386133 | 0.79 | HTR2C (0.69) | HTR2CHTR1APTGS2HTR7TAS1R3 | |
| SCHEMBL20083053 | 0.79 | HTR2C (0.34) | HTR2CNOTUMOPRL1 | |
| SCHEMBL43079 | 0.79 | HTR2C (0.67) | HTR2CPTGS2OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169931-B2 | Cell differentiation, cell proliferation | SHIONOGI & CO., LTD. (JP) | 2007-01-30 | — | — | US | disclosed |
| US-7169931-B2 | Cell differentiation, cell proliferation | SHIONOGI & CO., LTD. (JP) | 2007-01-30 | — | — | US | disclosed |
| EP-0347690-B1 | PROCESS FOR MANUFACTURING BENZENE DERIVATIVES, AND BENZENE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1992-10-21 | — | — | EP | disclosed |
| US-5151548-A | Crop protection agents | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-29 | — | — | US | disclosed |
| EP-0347690-A2 | Process for manufacturing benzene derivatives, and benzene derivatives | BASF Aktiengesellschaft (DE) | 1989-12-27 | — | — | EP | disclosed |