Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853517 | 0.91 | MEN1 (0.73) | MEN1KMT2AHTTPOLBTSHR | |
| SCHEMBL7366310 | 0.82 | TSHR (0.78) | MEN1KMT2AHTTPOLBTSHR | |
| SCHEMBL40679 | 0.76 | POLB (0.61) | MEN1KMT2APOLBGSK3BALDH1A1 | |
| SCHEMBL30905277 | 0.76 | POLB (0.82) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL26961314 | 0.75 | TSHR (0.53) | MEN1KMT2AHTTTSHRGSK3B | |
| SCHEMBL9628750 | 0.74 | GSK3B (0.44) | MEN1KMT2AGSK3BALDH1A1LMNA | |
| SCHEMBL9628891 | 0.73 | GSK3B (0.54) | MEN1KMT2AGSK3BALDH1A1MAPT | |
| SCHEMBL22275060 | 0.73 | HDAC1 (0.66) | MEN1KMT2AHTTALDH1A1NPSR1 | |
| SCHEMBL30808635 | 0.72 | MEN1 (0.62) | MEN1KMT2AHTTGSK3BNPSR1 | |
| SCHEMBL10574135 | 0.72 | GSK3A (0.70) | MEN1KMT2AHTTPOLBGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |