Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 7/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9630923 | 0.99 | FEN1 (0.47) | FEN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9629023 | 0.82 | FEN1 (0.46) | FEN1PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL9715619 | 0.81 | FEN1 (0.49) | FEN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9629996 | 0.81 | FEN1 (0.49) | FEN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9488229 | 0.81 | FEN1 (0.49) | FEN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9629791 | 0.80 | FEN1 (0.48) | FEN1PDE4APDE4BPDE4CPDE4D | |
| Water SCHEMBL9629048 | 0.80 | FEN1 (0.48) | FEN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9628941 | 0.77 | FEN1 (0.41) | FEN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10582954 | 0.75 | FEN1 (0.44) | FEN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10412161 | 0.74 | FEN1 (0.58) | FEN1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232328-B1 | ZWITTERIONIC BICYCLIC COMPOUNDS AND THEIR SALTS, SOLVATES, HYDRATES AND ESTERS | SCHERING CORPORATION (US) | 1992-04-15 | — | — | EP | claimed |
| EP-0338010-B1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF HYPERPROLIFERATE SKIN DISEASE | SCHERING CORPORATION (US) | 1992-02-05 | — | — | EP | claimed |