Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 7/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10353387 | 0.90 | NPC1 (0.47) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL88930 | 0.79 | AHR (0.42) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL8853443 | 0.72 | MEN1 (0.40) | MAPTNPC1MEN1RAB9AKMT2A | |
| SCHEMBL13477741 | 0.72 | MEN1 (0.32) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7347184 | 0.72 | MEN1 (0.32) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9630852 | 0.70 | MEN1 (0.32) | MEN1KMT2AALDH1A1 | |
| SCHEMBL255954 | 0.69 | TSHR (0.44) | MAPTTSHR | |
| SCHEMBL518954 | 0.67 | MAPT (1.00) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL2138422 | 0.67 | MAPT (0.92) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL28694707 | 0.67 | TSHR (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |