⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629046 | 0.80 | — | — | |
| SCHEMBL9627730 | 0.75 | — | — | |
| SCHEMBL27958322 | 0.72 | — | — | |
| SCHEMBL20880455 | 0.71 | — | — | |
| SCHEMBL5585337 | 0.65 | — | — | |
| SCHEMBL27978076 | 0.62 | — | — | |
| SCHEMBL5585803 | 0.61 | SOS1 (0.35) | — | |
| SCHEMBL22889629 | 0.61 | — | — | |
| SCHEMBL12059704 | 0.61 | — | — | |
| SCHEMBL18881131 | 0.60 | SOS1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275760-B1 | SUBSTITUTED PIPERIDINES OR AZEPINES, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) | 1992-04-01 | — | — | EP | disclosed |
| EP-0275760-A1 | Substituted piperidines or azepines, their preparation and their therapeutical use | RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) | 1988-07-27 | — | — | EP | disclosed |