Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627373 | 0.94 | ELANE (0.44) | SLC2A1ELANETSHRHTTGLA | |
| SCHEMBL9629350 | 0.90 | SLC2A1 (0.42) | SLC2A1ELANETSHRHTTGLA | |
| SCHEMBL9628205 | 0.88 | SLC2A1 (0.46) | SLC2A1TSHRHTTGLAL3MBTL1 | |
| SCHEMBL9627470 | 0.84 | HTT (0.59) | SLC2A1TSHRHTTGLAL3MBTL1 | |
| SCHEMBL10704565 | 0.84 | CNR1 (0.42) | ELANEHTTALDH1A1LMNACYP3A4 | |
| SCHEMBL9659886 | 0.84 | SLC2A1 (0.44) | SLC2A1ELANETSHRHTTGLA | |
| SCHEMBL9627455 | 0.83 | SLC2A1 (0.47) | SLC2A1TSHRHTTGLAL3MBTL1 | |
| SCHEMBL10705375 | 0.83 | CNR1 (0.43) | SLC2A1ELANEHTTL3MBTL1LMNA | |
| SCHEMBL9660009 | 0.83 | SLC2A1 (0.46) | SLC2A1TSHRHTTGLAALDH1A1 | |
| SCHEMBL9660454 | 0.82 | SLC2A1 (0.49) | SLC2A1TSHRHTTGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | claimed |
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |