Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | INMT | O95050 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853801 | 0.95 | HDAC1 (0.51) | HDAC1HDAC6NOTUMPOLBINMT | |
| SCHEMBL12649500 | 0.88 | POLB (0.52) | HDAC1HDAC6NOTUMPOLBTP53 | |
| SCHEMBL9628981 | 0.77 | NOTUM (0.47) | HDAC1HDAC6NOTUMINMTALDH1A1 | |
| SCHEMBL3795637 | 0.77 | KDM1A (0.40) | HDAC1HDAC6NOTUMPOLBTP53 | |
| SCHEMBL22275060 | 0.75 | HDAC1 (0.66) | HDAC1HDAC6TP53MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL3937688 | 0.75 | KDM1A (0.39) | HDAC1HDAC6NOTUMPOLBTP53 | |
| Bromide SCHEMBL4745574 | 0.75 | KDM1A (0.39) | HDAC1HDAC6NOTUMPOLBTP53 | |
| Iodide SCHEMBL3292671 | 0.75 | KDM1A (0.39) | HDAC1HDAC6NOTUMPOLBTP53 | |
| Bromide SCHEMBL1797567 | 0.75 | KDM1A (0.39) | HDAC1HDAC6NOTUMPOLBTP53 | |
| Iodide SCHEMBL28361954 | 0.75 | KDM1A (0.39) | HDAC1HDAC6NOTUMPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |