Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | ITGAL | P20701 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7135256 | 0.82 | ITGB2 (0.53) | TRPA1ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL8402593 | 0.77 | SMN1; SMN2 (0.59) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL8402596 | 0.77 | SMN1; SMN2 (0.59) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL17362386 | 0.77 | FEN1 (0.61) | — | |
| SCHEMBL17362389 | 0.77 | FEN1 (0.61) | — | |
| SCHEMBL24567560 | 0.76 | ITGB2 (0.48) | TRPA1ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL13761299 | 0.76 | NPSR1 (0.50) | TRPA1ITGB2ICAM1ITGAL | |
| SCHEMBL164814 | 0.76 | ITGB2 (0.48) | TRPA1ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL30771879 | 0.75 | SMN1; SMN2 (0.50) | MEN1KMT2AALDH1A1 | |
| SCHEMBL31125745 | 0.75 | SMN1; SMN2 (0.50) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323637-B1 | L(-) 2,6-DIFLUOROBENZOIC-N-(1,1,1-TRIFLUORO-PROP-2-YL)AMIDE | BAYER AG (DE) | 1992-12-16 | — | — | EP | claimed |
| US-4840969-A | APPLYING AS INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | claimed |
| EP-0323637-B1 | L(-) 2,6-DIFLUOROBENZOIC-N-(1,1,1-TRIFLUORO-PROP-2-YL)AMIDE | BAYER AG (DE) | 1992-12-16 | — | — | EP | disclosed |
| US-5082862-A | Insecticides, nematocides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | disclosed |
| EP-0323637-A1 | L(-) 2,6-difluorobenzoic-N-(1,1,1-trifluoro-prop-2-yl)amide | BAYER AG (DE) | 1989-07-12 | — | — | EP | disclosed |
| EP-0323637-A1 | L(-) 2,6-difluorobenzoic-N-(1,1,1-trifluoro-prop-2-yl)amide | BAYER AG (DE) | 1989-07-12 | — | — | EP | disclosed |
| US-4840969-A | APPLYING AS INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |