SCHEMBL9630278

SCHEMBL9630278

NN1C(=O)CCC1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE P12821 7/20 0.44
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GRM2 Q14416 1/20 0.33
GRM3 Q14832 1/20 0.33
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
HTT P42858 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRR1 P24046 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15338638 0.81 ACE (0.36) ACEKMT2A
SCHEMBL2345094 0.76 ACE (0.45) ACEMEN1KMT2AMMP2MMP9
SCHEMBL2345097 0.76 ACE (0.45) ACEMEN1KMT2AMMP2MMP9
SCHEMBL28228231 0.76 ACE (0.45) ACEMEN1KMT2AMMP2MMP9
SCHEMBL8213582 0.75 ACE (0.53) ACEMEN1KMT2AGRM2GRM3
SCHEMBL23211224 0.74 ACE (0.44) ACEMEN1KMT2AMMP2MMP9
SCHEMBL18832362 0.74 ACE (0.44) ACEMEN1KMT2AMMP2MMP9
SCHEMBL2715722 0.74 ACE (0.56) ACEMEN1KMT2AMMP2MMP9
SCHEMBL2805870 0.74 ACE (0.56) ACEMEN1KMT2AMMP2MMP9
SCHEMBL11707855 0.74 ACE (0.44) ACEMEN1KMT2AMMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0356665-B1 CATIONIC FIXATION COMPOSITION AND PROCESS FOR THE PERMANENT WAVING OF HAIR Wella Aktiengesellschaft (DE) 1992-06-03 EP claimed
WO-2023117783-A1 COSMETIC COMPOSITION COMPRISING PARTICULAR ANIONIC SURFACTANT(S), HYDROXYHYDROCARBYL (POLY)GLYCOSIDE(S) AND SPECIFIC CARBOXYLIC ACID(S) L'OREAL (FR) 2023-06-29 WO disclosed
CN-108610649-A Coupling agent 周宁 2018-10-02 CN disclosed
CN-102387854-B Water in oil emulsion, method for production thereof CLARIANT INT LTD 2014-03-05 CN disclosed
CN-102387854-A Water in oil emulsion, method for the production thereof CLARIANT INT LTD 2012-03-21 CN disclosed