Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.36 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630372 | 1.00 | RARB (0.43) | RARBFAAHSPHK1RARARARG | |
| SCHEMBL9630353 | 1.00 | RARB (0.43) | RARBFAAHSPHK1RARARARG | |
| SCHEMBL9632546 | 1.00 | RARB (0.43) | RARBFAAHSPHK1RARARARG | |
| SCHEMBL9630366 | 1.00 | RARB (0.43) | RARBFAAHSPHK1RARARARG | |
| SCHEMBL9632551 | 1.00 | RARB (0.43) | RARBFAAHSPHK1RARARARG | |
| SCHEMBL9631059 | 1.00 | RARB (0.43) | RARBFAAHSPHK1RARARARG | |
| SCHEMBL9631066 | 1.00 | RARB (0.43) | RARBFAAHSPHK1RARARARG | |
| SCHEMBL9406345 | 0.99 | RARB (0.41) | RARBFAAHSPHK1RARARARG | |
| SCHEMBL9406350 | 0.99 | RARB (0.41) | RARBFAAHSPHK1RARARARG | |
| SCHEMBL9630445 | 0.96 | RARB (0.41) | RARBFAAHSPHK1RARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364538-B1 | DIFLUOROBENZOL DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |