Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 3/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631304 | 0.98 | RARB (0.38) | RARBHSD11B1NPC1RAB9AFAAH | |
| SCHEMBL9630345 | 0.97 | RARB (0.39) | RARBFAAHITGB3ITGA2BSPHK1 | |
| SCHEMBL9630364 | 0.97 | RARB (0.39) | RARBFAAHITGB3ITGA2BSPHK1 | |
| SCHEMBL9632544 | 0.97 | RARB (0.39) | RARBFAAHITGB3ITGA2BSPHK1 | |
| SCHEMBL9631056 | 0.97 | RARB (0.39) | RARBFAAHITGB3ITGA2BSPHK1 | |
| SCHEMBL9631641 | 0.96 | RARB (0.38) | RARBHSD11B1NPC1RAB9AFAAH | |
| SCHEMBL9631142 | 0.95 | RARB (0.39) | RARBFAAHSPHK1RARARARG | |
| SCHEMBL9631468 | 0.94 | RARB (0.32) | RARBMPLHRH3 | |
| SCHEMBL9630243 | 0.94 | RARB (0.33) | RARBMPLITGB3ITGA2B | |
| SCHEMBL9632665 | 0.93 | RARB (0.35) | RARBFAAHMPLITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364538-B1 | DIFLUOROBENZOL DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |