Cyclopropane

Cyclopropane

SCHEMBL963062

C(OCC1CO1)C1CO1.C1CC1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.62
ALDH1A1 P00352 10/20 0.54
MAPK1 P28482 2/20 0.54
SMN1; SMN2 Q16637 3/20 0.52
TDP1 Q9NUW8 3/20 0.48
TP53 P04637 5/20 0.41
CYP3A4 P08684 2/20 0.41
HIF1A Q16665 2/20 0.38
GLA P06280 1/20 0.35
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
KMT2A Q03164 1/20 0.33
PPARG P37231 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
CHRM2 P08172 1/20 0.31
CHRM5 P08912 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL961313 1.00 TSHR (0.62) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
Cyclohexane SCHEMBL960269 1.00 TSHR (0.62) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL28515263 1.00 TSHR (0.62) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL8044179 1.00 TSHR (0.62) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL15245 0.94
SCHEMBL2933671 0.94
SCHEMBL2933673 0.94
SCHEMBL4623846 0.94
SCHEMBL4895623 0.94 TSHR (0.68) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
Methyl Alcohol SCHEMBL3660410 0.92 TSHR (0.54) TSHRALDH1A1MAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400530-A1 POLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Zhuhai Wango Chemical Co., Ltd. (CN) 2024-07-17 EP disclosed
EP-4400527-A1 SEMI-AROMATIC POLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Zhuhai Wango Chemical Co., Ltd. (CN) 2024-07-17 EP disclosed
EP-4400529-A1 SEMI-AROMATIC POLYETHER ESTER, PREPARATION METHOD THEREFOR AND USE THEREOF Zhuhai Wango Chemical Co., Ltd. (CN) 2024-07-17 EP disclosed
CN-115785413-B Biodegradable aliphatic polyester and preparation method and application thereof 金发科技股份有限公司 2024-07-12 CN disclosed
CN-118206726-A Aliphatic-aromatic copolyester and preparation method and application thereof 金发科技股份有限公司 2024-06-18 CN disclosed
CN-118185265-A Biodegradable polyester composition and application thereof 金发科技股份有限公司 2024-06-14 CN disclosed
WO-2024120311-A1 BIODEGRADABLE ALIPHATIC POLYESTER, AND PREPARATION METHOD THEREFOR AND USE THEREOF 金发科技股份有限公司 2024-06-13 WO disclosed
WO-2024120310-A1 BIODEGRADABLE POLYESTER COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF 金发科技股份有限公司 2024-06-13 WO disclosed
CN-115873222-B Biodegradable polyester composition and preparation method and application thereof 金发科技股份有限公司 2024-05-14 CN disclosed
EP-4174105-B1 SEMI-AROMATIC POLYESTER AND PREPARATION METHOD AND APPLICATION THEREOF JIANGSU KINGFA SCI & TECH ADV MAT CO LTD (CN) 2023-12-13 EP disclosed
EP-2213703-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION Teijin Chemicals, Ltd. (JP) 2010-08-04 EP disclosed
EP-2199456-A1 POLYESTER FIBER, PROCESS FOR PRODUCING THE SAME, AND TEXTILE STRUCTURE EMPLOYING THE SAME Toray Industries, Inc. (JP) 2010-06-23 EP disclosed
US-20100130651-A1 CRYSTALLINE POLYLACTIC ACID RESIN COMPOSITION AND PRODUCT MOLDED/FORMED THEREFROM UNITIKA LTD. (JP) 2010-05-27 US disclosed
CN-101469124-A Polycarbonate resin composition TEIJIN CHEMICALS LTD (JP) 2009-07-01 CN disclosed
CN-101374910-A Resin composition, molded article and their production methods TEIJIN CHEMICALS LTD (JP) 2009-02-25 CN disclosed
EP-1983030-A1 RESIN COMPOSITION, MOLDED ARTICLE AND THEIR PRODUCTION METHODS Teijin Chemicals, Ltd. (JP) 2008-10-22 EP disclosed
US-7351772-B2 Aliphatic polyester resin composition, preparation method thereof, and molded article and foamed article produced from the resin composition UNITIKA LTD. (JP) 2008-04-01 US disclosed
US-20060276617-A1 Aliphatic polyester resin composition, preparation method therefor, and molded article and foamed article produced from the resin composition UNITIKA LTD. (JP) 2006-12-07 US disclosed
EP-1640406-A1 ALIPHATIC POLYESTER RESIN COMPOSITION, METHOD FOR PRODUCTION THEREOF, MOLDED ARTICLE AND FOAMED ARTICLE COMPRISING THE RESIN COMPOSITION UNITIKA LTD. (JP) 2006-03-29 EP disclosed
WO-2000063313-A1 AQUEOUS COATING COMPOSITION IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 2000-10-26 WO disclosed