Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31508789 | 0.97 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL31508891 | 0.97 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL31508798 | 0.97 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL31509527 | 0.97 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL31508881 | 0.97 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL31509341 | 0.97 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7776563 | 0.97 | TSHR (0.43) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL11533275 | 0.97 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL6861326 | 0.97 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL31508932 | 0.97 | TSHR (0.50) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079249-A | Serotine antagonists at 5-HT2 level, antiallergens, antihistamines | ADIR ET COMPAGNIE (FR) | 1992-01-07 | — | — | US | disclosed |
| US-5071847-A | BIS (ARYL) ALKENE COMPOUNDS OF HOMOPIPERIDINES USEFUL AS SEROTONIN-ANTAGONISTS | ADIR ET COMPAGNIE (FR) | 1991-12-10 | — | — | US | disclosed |
| US-5028607-A | Antiserotonine agents | ADIR ET COMPAGNIE (FR) | 1991-07-02 | — | — | US | disclosed |
| EP-0145526-A2 | Allene-inhibiting agent for platinum catalysts, and polysiloxane compositions containing such an inhibitor | RHONE-POULENC CHIMIE (FR) | 1985-06-19 | — | — | EP | disclosed |