SCHEMBL9630684

SCHEMBL9630684

C/C1=C\CCC2OC2(C)CC/C=C(\C)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.44
ALDH1A1 P00352 4/20 0.44
LMNA P02545 3/20 0.44
TP53 P04637 3/20 0.44
NLRP3 Q96P20 2/20 0.44
NFKB1 P19838 2/20 0.44
CYP1A2 P05177 2/20 0.44
STAT6 P42226 2/20 0.44
MAPT P10636 2/20 0.44
PKM P14618 1/20 0.44
CASP1 P29466 1/20 0.44
PTGS2 P35354 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
CYP2D6 P10635 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
THPO P40225 1/20 0.44
HTT P42858 1/20 0.44
HIF1A Q16665 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9630687 1.00 CYP3A4 (0.44) CYP3A4ALDH1A1LMNATP53NLRP3
SCHEMBL9630691 1.00 CYP3A4 (0.44) CYP3A4ALDH1A1LMNATP53NLRP3
SCHEMBL21802956 1.00 CYP3A4 (0.44) CYP3A4ALDH1A1LMNATP53NLRP3
SCHEMBL23234194 0.94 CYP3A4 (0.43) CYP3A4ALDH1A1LMNATP53NLRP3
SCHEMBL3672742 0.91 CYP3A4 (0.41) CYP3A4ALDH1A1LMNATP53NLRP3
SCHEMBL3672743 0.91 CYP3A4 (0.41) CYP3A4ALDH1A1LMNATP53NLRP3
SCHEMBL3676277 0.91 CYP3A4 (0.48) CYP3A4ALDH1A1LMNATP53NLRP3
SCHEMBL3676278 0.91 CYP3A4 (0.48) CYP3A4ALDH1A1LMNATP53NLRP3
SCHEMBL17203745 0.88 STAT3 (0.41) CYP3A4ALDH1A1LMNATP53NLRP3
SCHEMBL20165805 0.88 STAT3 (0.41) CYP3A4ALDH1A1LMNATP53NLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0302993-B1 METHYLCYCLODODECATRIEN-1-OLS, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATION HAARMANN & REIMER GMBH (DE) 1992-05-06 EP claimed
US-4853368-A Methylcyclododecatri-2,5,9-en-1-ols, a process for their preparation, and their use HAARMANN & REIMER GMBH (DE) 1989-08-01 US claimed
EP-0302993-B1 METHYLCYCLODODECATRIEN-1-OLS, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATION HAARMANN & REIMER GMBH (DE) 1992-05-06 EP disclosed
US-4853368-A Methylcyclododecatri-2,5,9-en-1-ols, a process for their preparation, and their use HAARMANN & REIMER GMBH (DE) 1989-08-01 US disclosed
EP-0302993-A1 Methylcyclododecatrien-1-ols, method for their production and their application HAARMANN & REIMER GMBH (DE) 1989-02-15 EP disclosed