Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21496644 | 0.79 | CA12 (0.53) | MAPTALDH1A1KDM4ECA12CA9 | |
| SCHEMBL9629715 | 0.76 | SLC6A2 (0.43) | MAPTALDH1A1KDM4ECA12CA9 | |
| SCHEMBL20774262 | 0.73 | CA12 (0.50) | MAPTALDH1A1KDM4ECA12CA9 | |
| SCHEMBL7847932 | 0.72 | CA12 (0.49) | ALDH1A1CA12CA9POLB | |
| SCHEMBL30305756 | 0.71 | SLC6A2 (0.65) | KDM4ESLC6A3SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL9993898 | 0.71 | SLC6A2 (0.65) | KDM4ESLC6A3SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL1289661 | 0.71 | SLC6A2 (0.65) | KDM4ESLC6A3SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL12067661 | 0.71 | SLC6A2 (0.65) | KDM4ESLC6A3SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL799702 | 0.70 | DRD3 (0.45) | ALDH1A1CA12CA9DRD3 | |
| SCHEMBL14928448 | 0.70 | CYP1A2 (0.46) | MAPTALDH1A1CA12CA9DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377381-B1 | PROCESS FOR THE PREPARATION OF 1-PHENYL-1-DIETHYL AMINO-CARBONYL-2-PHTHALIMIDE METHYL CYCLOPROPANE Z | PIERRE FABRE MEDICAMENT (FR) | 1992-04-22 | — | — | EP | disclosed |
| EP-0377381-A1 | Process for the preparation of 1-phenyl-1-diethyl amino-carbonyl-2-phthalimide methyl cyclopropane Z | PIERRE FABRE MEDICAMENT (FR) | 1990-07-11 | — | — | EP | disclosed |