Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541597 | 0.83 | FGFR1 (0.64) | FGFR1KDM4EALOX15HTTMAPT | |
| Hydrochloric Acid SCHEMBL9631739 | 0.80 | FGFR1 (0.59) | FGFR1HCAR3HPGDGAAALDH1A1 | |
| SCHEMBL23675207 | 0.79 | HPGD (0.61) | FGFR1KDM4EALOX15HTTMAPT | |
| SCHEMBL11679816 | 0.79 | FGFR1 (0.60) | FGFR1KDM4EMAPTRAB9AHPGD | |
| SCHEMBL30158973 | 0.78 | GAA (0.61) | FGFR1RAB9AHPGDGAAALDH1A1 | |
| SCHEMBL9632294 | 0.78 | FGFR1 (0.59) | FGFR1KDM4EALOX15HTTMAPT | |
| Sulfuric Acid SCHEMBL7327338 | 0.78 | FGFR1 (0.59) | FGFR1KDM4EALOX15HTTMAPT | |
| SCHEMBL2340072 | 0.78 | FGFR1 (0.77) | FGFR1MAPTRAB9AHPGDALDH1A1 | |
| SCHEMBL2570944 | 0.77 | FGFR1 (1.00) | FGFR1MAPTRAB9AHPGDGSK3B | |
| SCHEMBL1307034 | 0.77 | FGFR1 (0.57) | FGFR1KDM4EHTTMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324988-B1 | 4-CHLOR-3-SULFAMOYL BENZOIC ACID HYDRAZIDES, PROCESS FOR THEIR PREPARATION, MEDICINES CONTAINING THEM AND USE OF THESE COMPOUNDS IN THE PREPARATION OF DIURETIC AND SALT REDUCING ACTIVITY MEDICINES | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1992-04-29 | — | — | EP | disclosed |
| US-4916149-A | Diuretic and saluretic 4-chloro-3-sulfamoylbenzoic acid hydrazides | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1990-04-10 | — | — | US | disclosed |