Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631193 | 1.00 | MAPT (0.37) | MAPTGAAMEN1KMT2AHPGD | |
| SCHEMBL9406190 | 1.00 | MAPT (0.37) | MAPTGAAMEN1KMT2AHPGD | |
| SCHEMBL9406187 | 1.00 | MAPT (0.37) | MAPTGAAMEN1KMT2AHPGD | |
| SCHEMBL9406332 | 0.99 | MAPT (0.38) | MAPTGAAMEN1KMT2AHPGD | |
| SCHEMBL9405950 | 0.99 | MAPT (0.36) | MAPTGAAMEN1KMT2AHPGD | |
| SCHEMBL8455394 | 0.99 | MAPT (0.38) | MAPTGAAMEN1KMT2AHPGD | |
| SCHEMBL8455398 | 0.99 | MAPT (0.38) | MAPTGAAMEN1KMT2AHPGD | |
| SCHEMBL9405949 | 0.99 | MAPT (0.36) | MAPTGAAMEN1KMT2AHPGD | |
| SCHEMBL9405746 | 0.99 | MAPT (0.38) | MAPTGAAMEN1KMT2AHPGD | |
| SCHEMBL9406329 | 0.99 | MAPT (0.38) | MAPTGAAMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364538-B1 | DIFLUOROBENZOL DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |