Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.31 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631254 | 1.00 | SCN9A (0.33) | SCN9APPARGCYP2C9CNR1CNR2 | |
| SCHEMBL19985184 | 0.99 | CNR1 (0.34) | SCN9APPARGCYP2C9CNR1CNR2 | |
| SCHEMBL19985201 | 0.99 | CNR1 (0.34) | SCN9APPARGCYP2C9CNR1CNR2 | |
| SCHEMBL9630583 | 0.99 | CNR1 (0.34) | SCN9APPARGCYP2C9CNR1CNR2 | |
| SCHEMBL19985174 | 0.99 | CNR1 (0.34) | SCN9APPARGCYP2C9CNR1CNR2 | |
| SCHEMBL9630574 | 0.99 | CNR1 (0.34) | SCN9APPARGCYP2C9CNR1CNR2 | |
| SCHEMBL26209558 | 0.96 | SCN9A (0.36) | SCN9APPARGCYP2C9CNR1CNR2 | |
| SCHEMBL14235296 | 0.96 | SCN9A (0.36) | SCN9APPARGCYP2C9CNR1CNR2 | |
| SCHEMBL9631624 | 0.96 | SCN9A (0.35) | SCN9APPARGCYP2C9CNR1CNR2 | |
| SCHEMBL9631628 | 0.96 | SCN9A (0.35) | SCN9APPARGCYP2C9CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364538-B1 | DIFLUOROBENZOL DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |