⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314057 | 0.80 | TSHR (0.36) | — | |
| SCHEMBL2539602 | 0.78 | GAA (0.42) | — | |
| SCHEMBL22018439 | 0.77 | TDP1 (0.44) | — | |
| SCHEMBL460908 | 0.76 | — | — | |
| SCHEMBL1965844 | 0.76 | — | — | |
| SCHEMBL842414 | 0.74 | — | — | |
| SCHEMBL1965842 | 0.74 | — | — | |
| Fluoride SCHEMBL22583589 | 0.74 | GLRA1 (0.41) | — | |
| SCHEMBL19576149 | 0.73 | EPHX1 (0.47) | — | |
| SCHEMBL862169 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104080783-A | Pyrrole compounds | YAKULT HONSHA KK | 2014-10-01 | — | — | CN | disclosed |
| CN-1077110-C | 13-substituted milbemycin 5-oxime derivatives their preparation and their use against insects and other pests | SANKYO CO (JP) | 2002-01-02 | — | — | CN | disclosed |
| CN-1153177-A | 13-substituted milbemycin 5-oxime derivatives their preparation and their use against insects and other pests | SANKYO CO (JP) | 1997-07-02 | — | — | CN | disclosed |
| EP-0285270-B1 | A METHOD FOR PRODUCING 1-PROPARGYL-2,4-DIOXOIMIDAZOLIDINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-03 | — | — | EP | disclosed |
| US-4827020-A | Propargyl amide precursor to 1-propargyl-2,4-dioxoimidazolidine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-05-02 | — | — | US | disclosed |
| WO-1989001934-A1 | HYDANTOIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-09 | — | — | WO | disclosed |
| EP-0285270-A1 | A method for producing 1-propargyl-2,4-dioxoimidazolidine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-10-05 | — | — | EP | disclosed |