Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632578 | 0.91 | MCL1 (0.45) | MCL1PPARGMEN1KMT2AMAPT | |
| SCHEMBL9632584 | 0.91 | MCL1 (0.45) | MCL1PPARGMEN1KMT2AMAPT | |
| SCHEMBL9633228 | 0.90 | PPARG (0.44) | MCL1PPARGMEN1KMT2AMAPT | |
| SCHEMBL9630963 | 0.90 | MCL1 (0.47) | MCL1PPARGMEN1KMT2AMAPT | |
| SCHEMBL9632239 | 0.86 | MEN1 (0.55) | MCL1PPARGMEN1KMT2AMAPT | |
| SCHEMBL9631379 | 0.82 | PPARG (0.42) | MCL1PPARGMEN1KMT2AMAPT | |
| SCHEMBL9631382 | 0.82 | PPARG (0.42) | MCL1PPARGMEN1KMT2AMAPT | |
| SCHEMBL8459669 | 0.82 | MEN1 (0.53) | PPARGMEN1KMT2AMAPTTDP1 | |
| SCHEMBL9633298 | 0.82 | MCL1 (0.43) | MCL1PPARGMEN1KMT2AMAPT | |
| SCHEMBL9633292 | 0.82 | MCL1 (0.43) | MCL1PPARGMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |