Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CCR3 | P51677 | 2/20 | 0.62 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1411499 | 0.80 | OPRL1 (1.00) | OPRL1POLBCCR3LTA4HDRD4 | |
| SCHEMBL3898508 | 0.79 | OPRL1 (0.79) | OPRL1POLBCCR3DRD4KDM4E | |
| SCHEMBL27679284 | 0.78 | OPRL1 (0.77) | OPRL1POLBCCR3LTA4HDRD4 | |
| SCHEMBL3890625 | 0.77 | OPRL1 (0.82) | OPRL1POLBCCR3DRD4KDM4E | |
| SCHEMBL653218 | 0.77 | CCR3 (1.00) | OPRL1POLBCCR3DRD4KDM4E | |
| SCHEMBL6042128 | 0.77 | OPRL1 (0.75) | OPRL1POLBCCR3LTA4HDRD4 | |
| SCHEMBL3235714 | 0.76 | OPRL1 (0.79) | OPRL1POLBCCR3LTA4HDRD4 | |
| SCHEMBL15530820 | 0.76 | OPRL1 (0.79) | OPRL1POLBCCR3LTA4HDRD4 | |
| SCHEMBL2591097 | 0.76 | OPRL1 (0.79) | OPRL1POLBCCR3DRD4KDM4E | |
| SCHEMBL6110923 | 0.76 | OPRL1 (0.79) | OPRL1POLBCCR3DRD4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153210-A | Hypoglycemic agent, animal growth regulator; veterinary medicine | BEECHAM GROUP P.L.C. (GB) | 1992-10-06 | — | — | US | disclosed |
| EP-0236624-A2 | Substituted phenyl ethanol amines, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-09-16 | — | — | EP | disclosed |