Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631110 | 0.99 | CNR1 (0.32) | SCN9ACNR1CNR2FPR2HTR1D | |
| SCHEMBL9631940 | 0.97 | SCN9A (0.34) | SCN9AHTR1DHTR1BALOX5APFEN1 | |
| SCHEMBL9631259 | 0.93 | HTR2C (0.33) | FPR2HTR1DHTR1BALOX5APFEN1 | |
| SCHEMBL9632570 | 0.92 | PPARG (0.33) | SCN9ACNR1CNR2FPR2HTR1D | |
| SCHEMBL9632018 | 0.92 | PPARG (0.33) | SCN9ACNR1CNR2FPR2HTR1D | |
| SCHEMBL9630340 | 0.92 | PPARG (0.33) | SCN9ACNR1CNR2FPR2HTR1D | |
| SCHEMBL9630338 | 0.92 | SCN9A (0.35) | SCN9ACNR1CNR2FPR2HTR1D | |
| SCHEMBL9630343 | 0.92 | SCN9A (0.35) | SCN9ACNR1CNR2FPR2HTR1D | |
| SCHEMBL9406275 | 0.91 | GAA (0.33) | SCN9ACNR1CNR2FPR2 | |
| SCHEMBL9406358 | 0.91 | GAA (0.33) | SCN9ACNR1CNR2FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364538-B1 | DIFLUOROBENZOL DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |