SCHEMBL9633095

SCHEMBL9633095

O=C(O)c1ccc2c(c1)C(=O)N(c1ccc(S(=O)(=O)c3ccc(N4C(=O)c5ccc(C(=O)O)cc5C4=O)cc3)cc1)C2=O

nearest known ligand 0.80

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 9/20 0.80
CA1 P00915 8/20 0.80
CA2 P00918 6/20 0.80
CA4 P22748 5/20 0.80
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
GFER P55789 1/20 0.63
ALDH1A1 P00352 2/20 0.62
NPSR1 Q6W5P4 2/20 0.62
CA12 O43570 6/20 0.61
SCN2A Q99250 1/20 0.58
MAPT P10636 2/20 0.56
POLB P06746 2/20 0.56
RAB9A P51151 1/20 0.56
CA7 P43166 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10388029 0.91 CA9 (0.67) CA9CA1CA2CA4MEN1
SCHEMBL9339007 0.89 CA9 (0.77) CA9CA1CA2CA4MEN1
SCHEMBL4234750 0.88 CA9 (0.77) CA9CA1CA2CA4MEN1
SCHEMBL9458657 0.85 CA1 (0.62) CA9CA1CA2CA4MEN1
SCHEMBL9742475 0.84 CA9 (0.71) CA9CA1CA2CA4MEN1
SCHEMBL8066756 0.83 ESR1 (0.70) CA9CA1CA2CA4MEN1
SCHEMBL5010584 0.83 CA9 (0.85) CA9CA1CA2CA4MEN1
SCHEMBL1618163 0.83 KMT2A (0.76) CA9CA1CA2CA4MEN1
SCHEMBL22523866 0.82 CA9 (0.68) CA9CA1CA2CA4MEN1
SCHEMBL4725618 0.82 CA9 (0.69) CA9CA1CA2CA4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0258767-B1 WHOLLY AROMATIC THERMOTROPIC POLYESTERS BASF Aktiengesellschaft (DE) 1992-06-24 EP disclosed
US-5092890-A Thermotropic mesomorphic polymer, apatite, filler BASF AKTIENGESELLSCHAFT (DE) 1992-03-03 US disclosed
US-RE33315-E Wholly aromatic mesomorphic polyester amide imides and the preparation thereof BASF AKTIENGESELLSCHAFT (DE) 1990-08-28 US disclosed
US-4801676-A MOLDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 1989-01-31 US disclosed
US-4788272-A WEAR RESISTANCE BASF AKTIENGESELLSCHAFT (DE) 1988-11-29 US disclosed
US-4762906-A Wholly aromatic mesomorphic polyether ester imide and the preparation thereof BASF AKTIENGESELLSCHAFT (DE) 1988-08-09 US disclosed
US-4728714-A Wholly aromatic mesomorphic polyester imides, the preparation and use thereof BASF AKTIENGESELLSCHAFT (DE) 1988-03-01 US disclosed
US-4728713-A Wholly aromatic mesomorphic polyester imides and the preparation thereof BASF AKTIENGESELLSCHAFT (DE) 1988-03-01 US disclosed
US-4727129-A Wholly aromatic mesomorphic polyester amide imides and the preparation thereof BASF AKTIENGESELLSCHAFT (DE) 1988-02-23 US disclosed
EP-0231468-A2 Liquid crystal polycondensates containing carbamide groups, their preparation and their use BASF Aktiengesellschaft (DE) 1987-08-12 EP disclosed
EP-0074551-B1 MOULDING MASS CONTAINING TRIKETOIMIDAZOLIDINE PRECONDENSATES, THEIR USE AND PROCESS FOR THE PREPARATION OF A TRIKETOIMIDAZOLIDINE PRECONDENSATE COMPOSITE SUITED FOR IT HOECHST AKTIENGESELLSCHAFT (DE) 1986-07-16 EP disclosed
US-4497915-A Molding compositions containing triketoimidazolidine precondensates, their use, and a process for preparing a triketoimidazolidine precondensate composite suitable for this purpose HOECHST AKTIENGESELLSCHAFT (DE) 1985-02-05 US disclosed
US-4483947-A Molding compositions containing triketoimidazolidine precondensates, their use, and a process for preparing a triketoimidazolidine precondensate composite suitable for this purpose HOECHST AKTIENGESELLSCHAFT (DE) 1984-11-20 US disclosed