Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3388482 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL11694296 | 0.95 | — | — | |
| Iodide SCHEMBL9349939 | 0.79 | — | — | |
| SCHEMBL10657155 | 0.76 | — | — | |
| Iodide SCHEMBL11062984 | 0.75 | — | — | |
| Bromide SCHEMBL9349302 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL28024400 | 0.74 | — | — | |
| SCHEMBL14218 | 0.72 | — | — | |
| SCHEMBL23714808 | 0.71 | — | — | |
| Iodide SCHEMBL31289773 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357192-B1 | PROCESS FOR PREPARING SUBSTITUTED GUANYLTHIOUREAS | PFIZER INC. (US) | 1992-05-06 | — | — | EP | disclosed |
| EP-0357192-A1 | Process for preparing substituted guanylthioureas | PFIZER INC. (US) | 1990-03-07 | — | — | EP | disclosed |