SCHEMBL9633459

SCHEMBL9633459

CCOC(=O)C(C)Oc1ccc2ccc(Oc3ccc(C(F)(F)F)cc3Cl)cc2c1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.52
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
TTR P02766 1/20 0.46
PPOX P50336 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MRGPRX4 Q96LA9 3/20 0.43
IDH1 O75874 1/20 0.43
PPARD Q03181 1/20 0.43
PPARA Q07869 1/20 0.43
HTR2A P28223 2/20 0.42
SLC6A4 P31645 2/20 0.42
KCNH2 Q12809 2/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10644204 1.00 FFAR1 (0.52) FFAR1KMT2AMEN1TTRPPOX
SCHEMBL9714362 0.98 FFAR1 (0.54) FFAR1KMT2AMEN1TTRPPOX
SCHEMBL10642868 0.96 FFAR1 (0.48) FFAR1KMT2AMEN1TTRPPOX
SCHEMBL10643786 0.96 FFAR1 (0.48) FFAR1KMT2AMEN1TTRPPOX
SCHEMBL10644966 0.93 FFAR1 (0.48) FFAR1KMT2AMEN1TTRPPOX
SCHEMBL10643331 0.92 FFAR1 (0.50) FFAR1KMT2AMEN1TTRPPOX
SCHEMBL10644002 0.92 FFAR1 (0.50) FFAR1KMT2AMEN1TTRPPOX
SCHEMBL10643884 0.92 FFAR1 (0.52) FFAR1KMT2AMEN1TTRPPOX
SCHEMBL10646108 0.92 FFAR1 (0.52) FFAR1KMT2AMEN1TTRPPOX
SCHEMBL10963334 0.91 FFAR1 (0.58) FFAR1KMT2AMEN1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0179015-B1 7-(ARYLOXY)-2-NAPHTHOXYALKANECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION OF THESE COMPOUNDS, AS WELL AS AGENTS HAVING HERBICIDAL ACTIVITY CONTAINING THESE COMPOUNDS SCHERING AKTIENGESELLSCHAFT (DE) 1988-04-13 EP claimed
US-4709077-A 7-(aryloxy)-2-naphthoxyalkanecarboxylic acid derivatives, processes for the preparation of these compounds, as well as agents having herbicidal activity containing these compounds SCHERING AKTIENGESELLSCHAFT (DE) 1987-11-24 US claimed
US-5166402-A Herbicidal α-(5-aryloxy-naphthalen-1-yl-oxy)-propionic acid derivatives BAYER AKTIENGESELLSCHAFT (DE) 1992-11-24 US disclosed
US-5129944-A HERBICIDAL ARYLOXYNAPHTHALENE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1992-07-14 US disclosed
EP-0309864-B1 ALPHA-(5-ARYLOXY-NAPHTHALEN-1-YL-OXY)-PROPIONIC-ACID DERIVATIVES BAYER AG (DE) 1991-05-22 EP disclosed
EP-0415212-A1 Aryloxynaphthalene derivatives BAYER AG (DE) 1991-03-06 EP disclosed
US-4994601-A Postemergence herbicides BAYER AKTIENGESELLSCHAFT (DE) 1991-02-19 US disclosed
EP-0309864-A1 Alpha-(5-aryloxy-naphthalen-1-yl-oxy)-propionic-acid derivatives BAYER AG (DE) 1989-04-05 EP disclosed
EP-0179015-B1 7-(ARYLOXY)-2-NAPHTHOXYALKANECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION OF THESE COMPOUNDS, AS WELL AS AGENTS HAVING HERBICIDAL ACTIVITY CONTAINING THESE COMPOUNDS SCHERING AKTIENGESELLSCHAFT (DE) 1988-04-13 EP disclosed
US-4709077-A 7-(aryloxy)-2-naphthoxyalkanecarboxylic acid derivatives, processes for the preparation of these compounds, as well as agents having herbicidal activity containing these compounds SCHERING AKTIENGESELLSCHAFT (DE) 1987-11-24 US disclosed
EP-0179015-A1 7-(Aryloxy)-2-naphthoxyalkanecarboxylic acid derivatives, processes for the preparation of these compounds, as well as agents having herbicidal activity containing these compounds SCHERING AKTIENGESELLSCHAFT (DE) 1986-04-23 EP disclosed