Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | BLM | P54132 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.69 |
| ▸ | FAAH | O00519 | 1/20 | 0.69 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.69 |
| ▸ | CNR2 | P34972 | 1/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.65 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490705 | 1.00 | CNR1 (0.76) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL11075672 | 1.00 | CNR1 (0.76) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL30078574 | 0.99 | CNR1 (0.74) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL23492978 | 0.94 | EPHX2 (0.72) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL30802593 | 0.94 | EPHX2 (0.72) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL2328289 | 0.94 | EPHX2 (0.72) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL2220077 | 0.94 | EPHX2 (0.72) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL18863614 | 0.94 | EPHX2 (0.72) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL9803815 | 0.94 | EPHX2 (0.72) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL9803810 | 0.94 | EPHX2 (0.72) | CNR1ALDH1A1HPGDTRPV1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |