Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633483 | 1.00 | CA1 (0.51) | CA1CA2CA4CA7MEN1 | |
| SCHEMBL18660291 | 0.84 | CA1 (0.59) | CA1CA2CA4CA7MEN1 | |
| SCHEMBL18660293 | 0.84 | CA1 (0.59) | CA1CA2CA4CA7MEN1 | |
| SCHEMBL3818880 | 0.84 | CA1 (0.52) | CA1CA2CA4CA7MEN1 | |
| SCHEMBL9723582 | 0.84 | CA1 (0.52) | CA1CA2CA4CA7MEN1 | |
| SCHEMBL3818882 | 0.84 | CA1 (0.52) | CA1CA2CA4CA7MEN1 | |
| SCHEMBL4549470 | 0.84 | CA1 (0.49) | CA1CA2CA4CA7MEN1 | |
| SCHEMBL9068333 | 0.84 | CA1 (0.52) | CA1CA2CA4CA7MEN1 | |
| SCHEMBL15047078 | 0.84 | CA1 (0.52) | CA1CA2CA4CA7MEN1 | |
| SCHEMBL9710814 | 0.84 | CA1 (0.49) | CA1CA2CA4CA7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116850-A | Insecticides | E. I. DU PONT DE NEMOURS AND CO. (US) | 1992-05-26 | — | — | US | disclosed |
| US-5091405-A | Insecticidal pyrazolines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0330678-B1 | INSECTICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-24 | — | — | EP | disclosed |
| EP-0393120-A1 | HETEROCYCLIC PYRAZOLINE CARBOXANILIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-24 | — | — | EP | disclosed |
| EP-0330678-A1 | INSECTICIDAL PYRAZOLINES. | DU PONT (US) | 1989-09-06 | — | — | EP | disclosed |
| WO-1989005300-A1 | HETEROCYCLIC PYRAZOLINE CARBOXANILIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-15 | — | — | WO | disclosed |
| WO-1988006583-A1 | INSECTICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |