⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443674 | 0.74 | — | — | |
| SCHEMBL7921744 | 0.73 | — | — | |
| SCHEMBL3722743 | 0.69 | — | — | |
| Ethylene SCHEMBL248596 | 0.67 | — | — | |
| SCHEMBL28645468 | 0.67 | HIF1A (0.44) | — | |
| SCHEMBL3955608 | 0.67 | — | — | |
| SCHEMBL29486936 | 0.67 | — | — | |
| SCHEMBL23130636 | 0.65 | HIF1A (0.41) | — | |
| SCHEMBL17613231 | 0.65 | HIF1A (0.41) | — | |
| SCHEMBL11990606 | 0.65 | HIF1A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483130-A1 | NOVEL ANTITUMOR ALDOPHOSPHAMIDE ANALOGS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-05-06 | — | — | EP | disclosed |
| US-5091552-A | Novel antitumor aldophosphamide analogs | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-02-25 | — | — | US | disclosed |
| US-5055459-A | Purging leukemic tumor cells from mammals | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS (US) | 1991-10-08 | — | — | US | disclosed |
| WO-1990010636-A1 | NOVEL ANTITUMOR ALDOPHOSPHAMIDE ANALOGS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1990-09-20 | — | — | WO | disclosed |
| US-4841085-A | ANTITUMOR AGENTS | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 1989-06-20 | — | — | US | disclosed |