⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14562801 | 1.00 | — | — | |
| SCHEMBL12159707 | 1.00 | — | — | |
| SCHEMBL9014214 | 0.84 | — | — | |
| SCHEMBL8506516 | 0.81 | — | — | |
| SCHEMBL10158349 | 0.78 | — | — | |
| SCHEMBL421883 | 0.78 | — | — | |
| SCHEMBL9616911 | 0.78 | — | — | |
| SCHEMBL1333585 | 0.78 | — | — | |
| SCHEMBL18557968 | 0.78 | — | — | |
| SCHEMBL8226932 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409505-B | Preparation method of posaconazole intermediate | 山东金城医药研究院有限公司 | 2023-10-17 | — | — | CN | claimed |
| CN-114409505-A | Preparation method of posaconazole intermediate | 山东金城医药研究院有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-114044766-A | Radioisotope carbon-14 labeled dinotefuran and intermediate, and preparation method and application thereof | 张北北九食品检验技术有限公司 | 2022-02-15 | — | — | CN | claimed |
| EP-2935278-B1 | TRICYCLIC COMPOUNDS FOR INHIBITING THE CFTR CHANNEL | NOVARTIS AG (CH) | 2017-03-15 | — | — | EP | claimed |
| US-9359381-B2 | Tricyclic compounds for inhibiting the CFTR channel | NOVARTIS AG (CH) | 2016-06-07 | — | — | US | claimed |
| US-20150336986-A1 | TRICYCLIC COMPOUNDS FOR INHIBITING THE CFTR CHANNEL | NOVARTIS AG (CH) | 2015-11-26 | — | — | US | claimed |
| EP-2935278-A1 | TRICYCLIC COMPOUNDS FOR INHIBITING THE CFTR CHANNEL | Novartis AG (CH) | 2015-10-28 | — | — | EP | claimed |
| WO-2014097148-A9 | TRICYCLIC COMPOUNDS FOR INHIBITING THE CFTR CHANNEL | NOVARTIS AG (CH) | 2015-02-19 | — | — | WO | claimed |
| WO-2014097148-A1 | TRICYCLIC COMPOUNDS FOR INHIBITING THE CFTR CHANNEL | NOVARTIS AG (CH) | 2014-06-26 | — | — | WO | claimed |
| US-20140171417-A1 | TRICYCLIC COMPOUNDS | NOVARTIS AG (CH) | 2014-06-19 | — | — | US | claimed |
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-114409505-B | Preparation method of posaconazole intermediate | 山东金城医药研究院有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-114409505-B | Preparation method of posaconazole intermediate | 山东金城医药研究院有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-114044766-B | Radioisotope carbon-14 labeled dinotefuran and intermediate, and preparation method and application thereof | 张北北九食品检验技术有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-114409505-A | Preparation method of posaconazole intermediate | 山东金城医药研究院有限公司 | 2022-04-29 | — | — | CN | disclosed |
| WO-1996017618-A1 | RADIOLABELED ANNEXIN-GALACTOSE CLUSTER CONJUGATES | NEORX CORPORATION (US) | 1996-06-13 | — | — | WO | disclosed |
| WO-1995032192-A1 | AROMATIC AMINE SUBSTITUTED BRIDGED NITROGEN AND SULFUR DONOR ATOM LIGANDS FOR IMAGING | NEORX CORPORATION (US) | 1995-11-30 | — | — | WO | disclosed |
| US-5432273-A | Cyclizing a 5-(protected)oxy-5-(heterocyclic base)-3(S)-fluoro-1,2-(S)-pentanediol | EMORY UNIVERSITY (US) | 1995-07-11 | — | — | US | disclosed |
| US-5414078-A | Preparation of 3'-substituted-2',3'-dideoxynucleosides and 2'-deoxynucleosides from acyclic, achiral precursors | EMORY UNIVERSITY (US) | 1995-05-09 | — | — | US | disclosed |
| WO-1992017485-A1 | PREPARATION OF 3'-SUBSTITUTED-2',3'-DIDEOXYNUCLEOSIDES AND 2'-DEOXYNUCLEOSIDES FROM ACYCLIC, ACHIRAL PRECURSORS | EMORY UNIVERSITY (US) | 1992-10-15 | — | — | WO | disclosed |