Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080243 | 0.88 | PLA2G4B (0.52) | PLA2G4BS1PR1NPC1RAB9AKDM4E | |
| SCHEMBL31365390 | 0.86 | S1PR1 (0.56) | PLA2G4BS1PR1NPC1RAB9AKDM4E | |
| SCHEMBL9344195 | 0.84 | RARB (0.56) | PLA2G4BS1PR1NPC1RAB9AKDM4E | |
| SCHEMBL9348830 | 0.84 | RARB (0.56) | PLA2G4BS1PR1NPC1RAB9AKDM4E | |
| SCHEMBL28160274 | 0.83 | MAPT (0.45) | PLA2G4BS1PR1NPC1RAB9AKDM4E | |
| SCHEMBL27865495 | 0.83 | MAPT (0.47) | PLA2G4BCYP2D6MAPK1CYP3A4MAPT | |
| SCHEMBL3383093 | 0.83 | PLA2G4B (0.48) | PLA2G4BS1PR1NPC1RAB9AKDM4E | |
| SCHEMBL5975726 | 0.83 | PLA2G4B (0.48) | PLA2G4BS1PR1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL17110450 | 0.83 | PLA2G4B (0.51) | PLA2G4BS1PR1NPC1RAB9AKDM4E | |
| SCHEMBL14142260 | 0.83 | PLA2G4B (0.51) | PLA2G4BS1PR1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171328-A | Polypiperidinyl derivatives; light, oxygen and heat resistance | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-15 | — | — | US | disclosed |