SCHEMBL9634578

SCHEMBL9634578

C=CC/C(C(=O)O)=C(\CCCCC)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.53
FNTB P49356 2/20 0.53
THRB P10828 1/20 0.53
PGGT1B P53609 1/20 0.53
AKR1B1 P15121 1/20 0.45
TSHR P16473 5/20 0.44
FAAH O00519 1/20 0.44
GPR84 Q9NQS5 7/20 0.43
PPARG P37231 7/20 0.43
PPARD Q03181 7/20 0.43
PPARA Q07869 7/20 0.43
HDAC11 Q96DB2 5/20 0.43
PTPN1 P18031 3/20 0.43
ALDH1A1 P00352 2/20 0.43
TLR2 O60603 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
FABP4 P15090 2/20 0.43
ALOX15 P16050 2/20 0.43
HSD17B10 Q99714 2/20 0.43
SLC22A6 Q4U2R8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9634593 1.00 FNTA (0.53) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL9139008 0.94 FNTA (0.46) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL7594856 0.85 FNTA (0.44) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL7594854 0.85 FNTA (0.44) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL555050 0.83 FNTA (0.71) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL183671 0.83 FNTA (0.71) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL555048 0.83 FNTA (0.71) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL1051704 0.81 FNTA (0.75) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL183951 0.81 FNTA (0.75) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL887162 0.81 FNTA (0.75) FNTAFNTBTHRBPGGT1BAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0267576-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF ALPHA-OLEFINS TO STEREOREGULAR POLYMERS HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION Himont Incorporated (US) 1992-05-27 EP disclosed
EP-0258089-B1 PROCESS FOR PREPARING SOLID COMPONENTS OF CATALYSTS, OR PRECURSORS OF SUCH COMPONENTS, IN THE FORM OF MICROSPHEROIDAL PARTICLES, SUITABLE FOR THE PREPARATION OF ETHYLENE POLYMERS Montedison S.p.A. (IT) 1990-10-24 EP disclosed
EP-0255790-B1 PROCESS FOR THE POLYMERIZATION OF ALPHA-OLEFINS OR OF THEIR MIXTURES WITH MINOR AMOUNTS OF ETHYLENE, BY MEANS OF CATALYSTS COMPRISING SOLID COMPONENTS OR PRECURSORS OF SUCH COMPONENTS, IN THE FORM OF MICROSPHEROIDAL PARTICLES Montedison S.p.A. (IT) 1990-10-03 EP disclosed
US-4855272-A Process for preparing solid components for catalysts, or precursors of such components, in the form of microspheroidal particles, suitable for the preparation of ethylene polymers MONTEDISON S.P.A. (IT) 1989-08-08 US disclosed
US-4804798-A Process for the polymerization of alpha-olefins or of their mixtures with minor amounts of ethylene, by means of catalysts comprising solid components or precursors and such components, in the form of microspheroidal particles MONTEDISON S.P.A. (IT) 1989-02-14 US disclosed
EP-0267576-A2 Components and catalysts for the polymerization of alpha-olefins to stereoregular polymers having narrow molecular weight distribution Himont Incorporated (US) 1988-05-18 EP disclosed
EP-0258089-A1 Process for preparing solid components of catalysts, or precursors of such components, in the form of microspheroidal particles, suitable for the preparation of ethylene polymers Montedison S.p.A. (IT) 1988-03-02 EP disclosed
EP-0255790-A1 Process for the polymerization of alpha-olefins or of their mixtures with minor amounts of ethylene, by means of catalysts comprising solid components or precursors of such components, in the form of microspheroidal particles Montedison S.p.A. (IT) 1988-02-10 EP disclosed