Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 6/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635773 | 0.96 | PDE3B (0.39) | MEN1POLBKMT2ACYP1A1CYP1A2 | |
| SCHEMBL9634529 | 0.91 | PDE3B (0.43) | MEN1POLBKMT2APDE3BPDE3A | |
| SCHEMBL9634591 | 0.90 | TOP1 (0.40) | CYP1A1CYP1A2CYP1B1PARP1PDE3B | |
| SCHEMBL9636063 | 0.90 | PDE5A (0.38) | MEN1POLBKMT2ACYP1A1CYP1A2 | |
| SCHEMBL9634942 | 0.88 | PDE3B (0.41) | CYP1A2PARP1PDE3BPDE3AP2RY12 | |
| SCHEMBL9634114 | 0.86 | PDE5A (0.41) | CYP1A1CYP1A2CYP1B1PARP1PDE3B | |
| SCHEMBL9634582 | 0.86 | PDE5A (0.40) | CYP1A1CYP1A2CYP1B1PDE3BPDE3A | |
| SCHEMBL9634873 | 0.86 | PDE5A (0.38) | MEN1POLBKMT2APDE3BPDE3A | |
| SCHEMBL9635731 | 0.85 | TOP1 (0.37) | CYP1A1CYP1A2CYP1B1PARP1PDE3B | |
| SCHEMBL9634126 | 0.85 | TOP1 (0.37) | CYP1A1CYP1A2CYP1B1PARP1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104881-A | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-04-14 | — | — | US | disclosed |
| US-4616090-A | 2-arylimidazopyridines intermediates | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-10-07 | — | — | US | disclosed |