Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 18/20 | 0.63 |
| ▸ | PDE2A | O00408 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 9/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.54 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636535 | 0.93 | PDE2A (0.62) | PDE5APDE2APDE4APDE4BPDE4C | |
| SCHEMBL9634375 | 0.90 | PDE2A (0.75) | PDE5APDE2APDE4APDE4BPDE4C | |
| SCHEMBL9634842 | 0.89 | PDE5A (0.63) | PDE5APDE2APDE4APDE4BPDE4C | |
| SCHEMBL9635720 | 0.88 | PDE2A (0.56) | PDE5APDE2APDE4APDE4BPDE4C | |
| SCHEMBL9634862 | 0.88 | PDE2A (0.56) | PDE5APDE2APDE4APDE4BPDE4C | |
| SCHEMBL9634691 | 0.87 | PDE2A (0.54) | PDE5APDE2APDE4APDE4BPDE4C | |
| SCHEMBL11772870 | 0.85 | PDE2A (0.82) | PDE5APDE2APDE4APDE4BPDE4C | |
| SCHEMBL9635743 | 0.85 | PDE2A (0.60) | PDE5APDE2APDE4APDE4BPDE4C | |
| SCHEMBL10741837 | 0.85 | PDE5A (0.42) | PDE5APDE2APDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL11769585 | 0.84 | PDE2A (0.80) | PDE5APDE2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104881-A | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-04-14 | — | — | US | disclosed |
| US-4616090-A | 2-arylimidazopyridines intermediates | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0072926-B1 | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GmbH (DE) | 1986-09-24 | — | — | EP | disclosed |