Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.41 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635236 | 0.84 | NOTUM (0.49) | NOTUMKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL9635018 | 0.77 | NOTUM (0.42) | NOTUMKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL7908917 | 0.72 | NOTUM (0.62) | NOTUMKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL30539320 | 0.72 | NOTUM (0.62) | NOTUMKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL10352868 | 0.70 | NOTUM (0.82) | NOTUMKDM4ELMNAHPGDL3MBTL1 | |
| SCHEMBL9628923 | 0.69 | NOTUM (0.79) | NOTUMKDM4ELMNAHPGDL3MBTL1 | |
| SCHEMBL27508975 | 0.69 | NOTUM (0.56) | NOTUMKDM4EALDH1A1RAB9ALMNA | |
| SCHEMBL31373871 | 0.68 | KDM4E (0.59) | NOTUMKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL18672305 | 0.68 | — | — | |
| SCHEMBL15524285 | 0.67 | NOTUM (0.73) | NOTUMKDM4ELMNAHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368063-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4990707-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0368063-A1 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |