Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.67 |
| ▸ | RARB | P10826 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.60 |
| ▸ | STS | P08842 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223346 | 1.00 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNPC1 | |
| SCHEMBL5222917 | 1.00 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNPC1 | |
| SCHEMBL5219396 | 1.00 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNPC1 | |
| SCHEMBL10808590 | 1.00 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNPC1 | |
| SCHEMBL5219438 | 1.00 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNPC1 | |
| SCHEMBL5215917 | 1.00 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNPC1 | |
| SCHEMBL14672532 | 1.00 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNPC1 | |
| SCHEMBL11126885 | 1.00 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNPC1 | |
| SCHEMBL5215164 | 1.00 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNPC1 | |
| SCHEMBL5220083 | 1.00 | TP53 (0.69) | TP53TSHRPLA2G4BRARBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301587-B1 | LIQUID CRYSTAL COMPOUNDS AND INTERMEDIATES THEREOF | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5114615-A | Compounds for optical apparatus | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0301587-A1 | Liquid crystal compounds and intermediates thereof | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-02-01 | — | — | EP | disclosed |