Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368293 | 0.82 | ELANE (0.62) | ELANE | |
| SCHEMBL17830878 | 0.80 | ELANE (0.40) | ELANEMEN1KMT2AESR1 | |
| SCHEMBL8668630 | 0.78 | ELANE (0.40) | ELANEMEN1KMT2A | |
| SCHEMBL7397916 | 0.73 | — | — | |
| SCHEMBL8371886 | 0.72 | ELANE (0.52) | ELANE | |
| SCHEMBL4344464 | 0.65 | ELANE (0.50) | ELANE | |
| SCHEMBL7324300 | 0.65 | ELANE (0.37) | ELANEMEN1KMT2AESR1 | |
| SCHEMBL7341895 | 0.65 | ELANE (0.50) | ELANE | |
| SCHEMBL7301346 | 0.64 | ELANE (0.34) | ELANEMEN1KMT2AESR1 | |
| SCHEMBL7443895 | 0.64 | ELANE (0.39) | ELANEMEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991004977-A1 | NOVEL 2-SPIROCYCLOPROPYL CEPHALOSPORIN SULFONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LABORATORIES, INC. (CA) | 1991-04-18 | — | — | WO | claimed |
| EP-0494914-A1 | NOVEL 2-SPIROCYCLOPROPYL CEPHALOSPORIN SULFONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LABORATORIES INC. (CA) | 1992-07-22 | — | — | EP | disclosed |
| WO-1991004977-A1 | NOVEL 2-SPIROCYCLOPROPYL CEPHALOSPORIN SULFONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LABORATORIES, INC. (CA) | 1991-04-18 | — | — | WO | disclosed |