Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28078345 | 0.98 | TSHR (0.56) | TSHRMEN1KMT2AHTTTHRB | |
| SCHEMBL8616123 | 0.94 | TSHR (0.52) | TSHRMEN1KMT2AHTTTHRB | |
| SCHEMBL9637326 | 0.94 | TSHR (0.56) | TSHRMEN1KMT2AHTTTHRB | |
| SCHEMBL11522848 | 0.87 | HTT (0.53) | TSHRMEN1KMT2AHTTTHRB | |
| SCHEMBL9502490 | 0.87 | TSHR (0.42) | TSHRHTTUSP2LPAR1LPAR3 | |
| SCHEMBL12653855 | 0.85 | TSHR (0.60) | TSHRMEN1KMT2AHTTTHRB | |
| SCHEMBL9061242 | 0.84 | TSHR (0.46) | TSHRMEN1KMT2AHTTTHRB | |
| SCHEMBL28534846 | 0.84 | TSHR (0.39) | TSHRHTTUSP2ALDH1A1LPAR1 | |
| SCHEMBL7197519 | 0.84 | HTT (0.59) | TSHRMEN1KMT2AHTTTHRB | |
| SCHEMBL11026183 | 0.82 | TSHR (0.47) | TSHRMEN1KMT2AHTTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252690-B1 | ANTISTATIC PLASTICISERS | BP Chemicals Limited (GB) | 1992-08-12 | — | — | EP | claimed |
| EP-0252690-A2 | Antistatic plasticisers | BP Chemicals Limited (GB) | 1988-01-13 | — | — | EP | claimed |