SCHEMBL9637533

SCHEMBL9637533

O=c1c2ccc3c4ccccc4sc4ccc(c2c43)c2nc3ccccc3n12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.57
KMT2A Q03164 5/20 0.56
MAPT P10636 4/20 0.56
MEN1 O00255 3/20 0.56
CYP1A2 P05177 2/20 0.56
CAMKK1 Q8N5S9 2/20 0.56
CAMKK2 Q96RR4 2/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
CASP1 P29466 1/20 0.56
CYP2C19 P33261 1/20 0.56
CASP7 P55210 1/20 0.56
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
CYP3A4 P08684 1/20 0.55
CSNK2A2 P19784 1/20 0.53
CSNK2B P67870 1/20 0.53
CSNK2A1 P68400 1/20 0.53
PIM3 Q86V86 1/20 0.53
DYRK2 Q92630 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25471259 0.87 BCL2 (0.43) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL29363030 0.85 BCL2 (0.68) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL7601022 0.85 BCL2 (0.68) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL29357905 0.85 BCL2 (0.68) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL7598227 0.85 BCL2 (0.68) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL269440 0.85 BCL2 (0.68) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL7599458 0.85 BCL2 (0.68) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL269002 0.85 BCL2 (0.68) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL7598251 0.85 BCL2 (0.68) BCL2KMT2AMAPTMEN1CYP1A2
SCHEMBL824450 0.84 BCL2 (0.70) BCL2KMT2AMAPTMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0281381-B1 ELECTROLUMINESCENT DEVICE WITH MODIFIED THIN FILM LUMINESCENT ZONE EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-07-15 EP disclosed
US-4933948-A Inclusion compound of cyclodextrin and fluorescent dye EASTMAN KODAK COMPANY (US) 1990-06-12 US disclosed
EP-0349265-A2 Electroluminescent devices EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-01-03 EP disclosed
US-4769292-A Electroluminescent device with modified thin film luminescent zone EASTMAN KODAK COMPANY (US) 1988-09-06 US disclosed