⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15839414 | 1.00 | — | — | |
| SCHEMBL9160 | 1.00 | — | — | |
| SCHEMBL15834095 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL29012664 | 0.97 | TSHR (0.42) | — | |
| Hydrochloric Acid SCHEMBL28215557 | 0.97 | TSHR (0.42) | — | |
| Water SCHEMBL28211091 | 0.97 | TSHR (0.42) | — | |
| SCHEMBL19368375 | 0.94 | TSHR (0.44) | — | |
| SCHEMBL167163 | 0.94 | TSHR (0.44) | — | |
| SCHEMBL11415551 | 0.88 | TSHR (0.40) | — | |
| SCHEMBL19368344 | 0.86 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119613-B1 | FLUOROMETRIC ASSAY OF TOTAL IGE LEVEL AND REAGENTS THEREFOR | BioWhittaker, Inc. (US) | 1992-07-29 | — | — | EP | disclosed |
| EP-0124103-B1 | FLUOROMETRIC ASSAY OF CHYMOPAPAIN AND REAGENTS THEREFOR | BioWhittaker, Inc. (US) | 1992-07-01 | — | — | EP | disclosed |
| US-5084379-A | Quantitative analysis of immunoglobulins | BIOWHITTAKER, INC. (US) | 1992-01-28 | — | — | US | disclosed |
| US-4963356-A | Stable antigenic extracts methods | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-10-16 | — | — | US | disclosed |
| EP-0107832-B1 | STABLE ALLERGENIC EXTRACTS AND METHODS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-09-19 | — | — | EP | disclosed |
| US-4844966-A | DIAGNOSING ALLERGIES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-07-04 | — | — | US | disclosed |
| US-4716120-A | PURIFICATION BY ULTRAFILTRATION AND ABSORPTION OF IMPURITIES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-12-29 | — | — | US | disclosed |
| EP-0124103-A2 | Fluorometric assay of chymopapain and reagents therefor | BioWhittaker, Inc. (US) | 1984-11-07 | — | — | EP | disclosed |
| EP-0119613-A2 | Fluorometric assay of total IgE level and reagents therefor | BioWhittaker, Inc. (US) | 1984-09-26 | — | — | EP | disclosed |
| EP-0107832-A2 | Stable allergenic extracts and methods | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-05-09 | — | — | EP | disclosed |
| US-4254082-A | Specific binding-adsorbent assay test means | MILES LABORATORIES, INC. (US) | 1981-03-03 | — | — | US | disclosed |
| US-4145406-A | SPECIFIC BINDING - ADSORBENT ASSAY METHOD AND TEST MEANS | MILES LABORATORIES, INC. (US) | 1979-03-20 | — | — | US | disclosed |